معرفی
Diletta Di Mitri serves as Associate Professor of Histology at Humanitas University and Group Leader of the Tumor Microenvironment Lab at Humanitas Research Hospital in Milan. Her dual appointment bridges academic instruction with cutting-edge cancer research within Italy's specialized hospital-research-teaching ecosystem.
Her research focuses on tumor-immune system interactions, particularly profiling immune cell dynamics in prostate cancer and melanoma using single-cell technologies. Key areas include:
- Tumor-associated macrophage reprogramming and lipid metabolism
- NK cell impairment mechanisms and therapeutic reactivation
- Immune microenvironment characterization via flow cytometry and spatial multiomics
Analysis of her 11 publications (2011-2023) reveals consistent focus on immune evasion mechanisms, with recent work (2022-2023) emphasizing macrophage lipid loading as a therapeutic target. Her research demonstrates strong translational potential, connecting basic immunology to clinical applications in solid tumors.
Scientific recognition includes:
- Pfizer Research Award (2015)
- Gerry Scotti Award (2018)
- Multiple best presentation awards (2008-2015)
- Best publication under 35 years in Switzerland (2015)
Funding from the European Union, Italian Association for Cancer Research (AIRC), and Italian Ministry of Health supports her laboratory's work. She mentors PhD students and postdocs while leading a multidisciplinary team including bioinformaticians and technicians. The Tumor Microenvironment Lab operates at Humanitas University Campus, utilizing advanced single-cell analysis platforms to develop novel immunotherapy strategies targeting cancer-immune crosstalk.
