Dianne Deplewski

Dianne Deplewski serves as an Associate Professor within the Department of Pediatrics-Endocrinology at the University of Chicago. Her academic and clinical work bridges molecular endocrinology and pediatric care, with over 30 years of research spanning sebaceous gland biology to contemporary metabolic disorders in children.

Her research portfolio prominently features pediatric obesity, type 1 and type 2 diabetes, polycystic ovary syndrome (PCOS), growth disorders, and vitamin D metabolism. Early career work established foundational knowledge on hormonal regulation of pilosebaceous unit development, particularly androgen and growth factor mechanisms in sebocyte differentiation. Current investigations focus on metabolic syndrome complications, endocrine management in inflammatory bowel disease, and rare diabetes presentations in adolescents.

Publication trends reveal a strategic evolution from basic science (1995-2007) exploring nuclear hormone receptors and lipogenic pathways to clinically oriented research (2014-2025) addressing obesity screening protocols, diabetes complications, and endocrine manifestations in genetic syndromes. Her 2023-2025 work includes high-impact case reports on atypical diabetes presentations and systematic reviews of metabolic consequences in pediatric populations.