David Walk

David Walk is a Professor in the Department of Neurology at the University of Minnesota Medical School, where he leads significant research initiatives in neuromuscular diseases. His work spans clinical neurology, inherited neuropathies, and amyotrophic lateral sclerosis (ALS), with a strong focus on clinical trials and translational research.

Research Interests:

• Amyotrophic Lateral Sclerosis (ALS)
• Inherited Neuropathies, including Charcot-Marie-Tooth disease
• Clinical Trial Readiness and Design
• Quantitative Sensory Testing and Intraepidermal Nerve Fiber Density
• Neuromuscular Symptom Evaluation and Management

His recent publications and projects highlight a strong emphasis on developing clinical guidelines, biorepositories, and natural history studies to advance therapeutic development for ALS and related disorders. He is actively involved in large-scale collaborative efforts such as the HEALEY ALS Platform Trial and the Inherited Neuropathy Consortium.

Scientific Contributions:

• Principal Investigator on multiple NIH- and foundation-funded grants
• Contributor to high-impact clinical trials in ALS
• Author of authoritative texts including the Clinical Handbook of Neuromuscular Medicine

Dr. Walk advises on clinical management strategies for genetic ALS/FTD risk and is committed to improving access and equity in ALS research through initiatives like Access for All in ALS (ALL ALS). He also leads biorepository efforts in Minnesota to support regional and national ALS research. His work contributes to UN Sustainable Development Goal 3: Good Health and Well-being.