David W. Appel

David W. Appel, M.D. is an Associate Professor in the Department of Medicine at Albert Einstein College of Medicine, specializing in Pulmonary Medicine. He practices at Montefiore Medical Center across multiple locations in the Bronx, NY, including the Medical Arts Pavilion and Hutch Tower II facilities. His clinical expertise spans sleep disorders and general pulmonary conditions, with extensive research investigating the interplay between respiratory physiology and systemic diseases.

His education includes:

• Medical Education: Albert Einstein College of Medicine
• Residency: Jacobi Medical Center
• Fellowship: Albert Einstein College of Medicine

Dr. Appel's research focuses on mechanistic relationships between sleep disorders and physiological responses, particularly: obstructive sleep apnea prediction using snoring/pharyngeal metrics; cough reflex modulation during sleep; gastroesophageal reflux in apnea patients; restless leg syndrome etiology; and cardiopulmonary interactions in heart failure and anemia. Current studies examine CPAP optimization, H.pylori/proton pump inhibitor effects on restless legs, hepcidin's role in apnea-related anemia, and racial disparities in sleep-disordered breathing outcomes.