معرفی
Dr. David Pitt is an Associate Professor of Neurology at Yale School of Medicine, specializing in multiple sclerosis (MS) and neurodegeneration. He leads the Pitt Lab, focusing on astrocyte and oligodendrocyte biology, neuroimaging biomarkers (e.g., QSM), and exosome-based diagnostics. His research integrates advanced techniques like single-nucleus RNA sequencing and multiplexed imaging to map cellular interactions in MS lesions. Key affiliations include the Center for Brain & Mind Health and the Yale Stem Cell Center.
Education:
- MD, Philipps University (Germany)
- Postdoctoral Fellowship, Albert Einstein College of Medicine
- Neurology Residency, Albert Einstein College of Medicine
- Neuroimmunology Fellowship, Washington University/Barnes-Jewish Hospital
Research Interests: MS neurodegeneration mechanisms, imaging of chronic active lesions, astrocyte-exosome biomarkers, and translational therapies. His lab develops novel techniques such as multiplexed antibody imaging and CRISPR-edited iPSC models.
Publications: Focus on QSM as an inflammatory biomarker, exosome-based diagnostics, and genetic risk variant effects on glial cells. Recent work emphasizes precision phenotyping and imaging consensus for MS lesion characterization.
Awards: Includes Postdoctoral Research Fellowship from the National MS Society (2005) and German Research Council scholarships (1998).
Grants & Teams: Collaborates with David Hafler and Erin Longbrake on MS immunology and clinical trials. Active in the Program for Neuroinflammation and translational imaging consortia.
Labs/Teams: Pitt Lab at Yale, specializing in neuroinflammation, imaging, and stem cell technologies. Key innovations include spatial mapping of lesional cells and exosome isolation protocols.
