David Michael Allman

David Michael Allman is a Professor in the Department of Pathology and Laboratory Medicine at the Perelman School of Medicine, University of Pennsylvania, where he also serves as Vice Chair for Faculty Development and Academic Affairs. His research focuses on B cell lineage differentiation, plasma cell survival mechanisms, and immunoregulatory networks.

• Education: BS in Microbiology (1982, Pennsylvania State University), PhD in Immunology (1993, University of Pennsylvania)
• Postgraduate Training: I.R.T.A. Fellow (NIH), Fox Chase Cancer Center Fellow (1996-99)

Research Themes include:

• Plasma Cell Longevity: Analyzing survival niches in bone marrow and gut mucosa, molecular pathways (e.g., mTORC1, unfolded protein response)
• B Cell Fate Regulation: Exploring transcription factors like EBF and YY1 in lineage commitment
• Vaccine Immunology: Developing lipid nanoparticle mRNA vaccines (e.g., Lyme disease) and understanding IgA-mediated mucosal-systemic immune links

Scientific Contributions span 30+ years, with key awards including the Edward David Lustbader Prize (1999), Leukemia and Lymphoma Society Scholar (2004-09), and multiple teaching accolades. His PubMed profile highlights recent work on neuroinflammation, sepsis, and transcriptional networks.