David Lupton

David Lupton is a Professor at the School of Chemistry, Monash University. His research is centered on catalysis, particularly organocatalysis and biocatalysis, with a strong emphasis on enantioselective transformations and fundamental reactivity. He leads a research group focused on discovering new catalytic methods to convert inexpensive chemicals into high-value compounds, contributing to sustainable chemical processes and future applications in medicinal chemistry.

• Position: Professor, School of Chemistry, Monash University
• Email: David.Lupton@monash.edu
• ORCID: 0000-0002-0958-4298
• Research Group: Lupton Group

David Lupton's research interests lie in the discovery of new catalytic reactivity, with a focus on:

• Organocatalysis and umpolung strategies
• Enantioselective synthesis
• Biocatalysis using F420-dependent enzymes
• Total synthesis of complex organic molecules
• Development of sustainable and efficient synthetic methodologies
• Applications in medicinal chemistry, including iridoid-based natural products

His recent publications highlight a strong trend in asymmetric catalysis, particularly through novel organocatalytic and biocatalytic methods. Articles in 2023 demonstrate expertise in N-heterocyclic carbene catalysis, enzyme-mediated ene-reductions, and the design of dimeric pharmaceuticals using cage hydrocarbons. His work bridges fundamental organic chemistry with practical applications in drug development and materials science.

David Lupton is actively involved in major research projects funded by the Australian Research Council (ARC), including:

• Hydrogen atom transfer via Proton Coupled Electron Transfer (2021–2025)
• Polarity inversion of conjugate acceptors: New opportunities in catalysis (2020–2025)
• Luminophores and Photochromes: Towards Molecular Componentry (2019–2023)
• C=C insertion, C-H bond functionalisation, challenges to organocatalysis (2017–2019)

He collaborates with institutions such as CSIRO, RMIT University, La Trobe University, and the University of Melbourne. His research contributes to UN Sustainable Development Goals, particularly in sustainable chemistry and health innovation. While no formal awards are listed in the provided text, his sustained funding and high-impact publications reflect significant recognition in the field.

David Lupton's research group, the Lupton Group, develops innovative technologies for accessing complex molecular families, enabling biological profiling and potential therapeutic applications. His vision emphasizes the long-term legacy of fundamental science, aiming to provide future generations with transformative chemical knowledge.