
معرفی
David Goltzman is a Professor in the Departments of Medicine and Physiology at McGill University. He serves as Director of the Centre for Advanced Bone and Periodontal Research and the Calcium Research Laboratory, located at the McGill University Health Centre - Glen site. His research focuses on hormonal factors influencing calcium homeostasis and skeletal metabolism, including parathyroid hormone, parathyroid hormone-like peptide, and calcitonin. Dr. Goltzman holds an MD from McGill University.
His research interests include endocrinology, bone metabolism, and molecular mechanisms underlying skeletal disorders such as osteoporosis. He has contributed to studies on vitamin D signaling pathways, senescence-related bone degeneration, and fracture risk prediction models. His work integrates molecular biology, clinical epidemiology, and advanced imaging techniques like HR-pQCT.
Dr. Goltzman has published extensively on topics including hormonal disorders (e.g., MEN1 syndromes), therapeutic targets for renal phosphate wasting, and global epidemiology of diabetes and bone diseases. His recent research highlights the role of Sirt1 and Nrf2 pathways in mitigating age-related bone loss and the development of novel diagnostic approaches using standard imaging.
While no specific scientific awards are listed, his leadership in bone research is evident through directorships of major research centers and high-impact publications. His work addresses both fundamental biological mechanisms and clinical applications in aging populations and metabolic disorders.
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