معرفی
David Bilder is a Professor of Molecular and Cell Biology at the University of California, Berkeley, with affiliations in the Division of Genetics. His research focuses on epithelial architecture, tumor suppression mechanisms, and morphogenetic processes in Drosophila. Key projects explore cell polarity regulation, epithelial-tumor interactions, and biomechanical forces in tissue development. His lab uses genetic screens and live imaging to study how polarity defects drive malignancy and how tumors induce systemic pathologies like cachexia.
Research interests include understanding how epithelial organization controls organ size, tumor progression, and host responses to cancer. His work bridges molecular cell biology with organismal physiology, leveraging Drosophila as a model system for translational insights into human diseases like cancer. Recent studies highlight roles of extracellular matrix stiffness in tissue elongation and systemic coagulopathy in tumor lethality.
Publications emphasize mechanistic links between polarity proteins (Scribble module), endocytic trafficking, and oncogenic pathways. The lab’s tools include novel cell migration tracking methods and genetically engineered tumor models. While no formal student advising list is provided, his work suggests leadership in training graduate students and postdocs in developmental and cancer biology.
