Daniel P Higgins

Daniel P Higgins is a Lecturer at the T.H. Chan School of Medicine, UMass Chan Medical School, affiliated with the Program in Molecular Medicine. His research bridges computational biology and molecular genetics, focusing on stress response mechanisms and gene regulation.

Education:

• Bachelor of Arts in Computer Science, Assumption College
• Master of Science in Computer Science, Georgia Institute of Technology

Dr. Higgins’s work centers on leveraging computational tools to study genetic networks and metabolic pathways, particularly in Caenorhabditis elegans. His recent studies examine oxidative stress adaptation, S-adenosylmethionine (SAM) metabolism, and mitochondrial function. He developed the WormCat platform for genome-scale data analysis, advancing functional annotation in nematode genetics.

The most recent publications highlight a focus on transcriptional regulation, GPCR signaling, and phosphatidylcholine-mitochondria interplay. His earlier work established foundational insights into SAM-dependent stress responses.

Networks & Collaborations: Dr. Higgins collaborates with researchers like Amy Walker and Read Pukkila-Worley, contributing to interdisciplinary studies in systems biology. His work intersects with concepts such as genome annotation, molecular signaling, and bioinformatic tools.