Arnaud Ahier

Dr. Arnaud Ahier is a Research Fellow at the Queensland Brain Institute (QBI), The University of Queensland. His research focuses on molecular mechanisms underlying cell plasticity, mitochondrial biology, and genetic regulation in developmental and disease contexts. He employs Caenorhabditis elegans as a primary model organism to study transdifferentiation events, mitochondrial quality control, and epigenetic regulation.

Key research interests include:

• Regulation of mitochondrial DNA dynamics and stress responses
• Cellular reprogramming through transdifferentiation
• Role of Notch signaling and histone modifiers in developmental plasticity
• Genetic mosaicism and organism-wide mitochondrial distribution

His work bridges fundamental biology with translational implications, particularly in neurodegenerative diseases (e.g., Parkinson's) and parasitic infections (e.g., schistosomiasis). Recent studies highlight mitochondrial 6mA modifications in aging processes and PINK1/parkin pathways in mitochondrial quality control.

Dr. Ahier has developed innovative methodologies including CS-MAP (Cell-Specific Mitochondria Affinity Purification) for studying mitochondria in vivo. His publications span high-impact journals like Nature Communications, Science, and Cell Metabolism.

Collaborative research includes partnerships with Steven Zuryn (mitochondrial biology) and Sophie Jarriault (cell reprogramming). Current projects explore mitochondrial epigenetics, aging mechanisms, and signaling pathways in cellular plasticity.