معرفی
Daniel Lafontaine is a Professor in the Department of Biology at the University of Sherbrooke, specializing in molecular and cellular biology with a focus on RNA-based gene regulation mechanisms.
Education:
- B.Sc. in Biochemistry, University of Sherbrooke (1994)
- Ph.D. in Biochemistry, University of Sherbrooke (1999)
- Postdoctoral Fellowship, University of Dundee, Scotland (1999-2002)
Research Interests: Dr. Lafontaine's work centers on riboswitches—non-coding RNA elements that directly sense cellular metabolites to regulate gene expression through transcriptional and translational control. His laboratory employs Fluorescence Resonance Energy Transfer (FRET) to analyze RNA conformational changes during metabolite binding, investigating how riboswitch folding dynamics govern genetic regulation in bacteria and eukaryotes. This research has implications for developing novel antimicrobial agents targeting essential metabolic pathways.
Laboratory: He leads an active research group (Page du laboratoire) utilizing multidisciplinary approaches to study riboswitch mechanisms and engineer synthetic genetic control elements.
