معرفی
Ronald Breaker is a Sterling Professor of Molecular, Cellular, and Developmental Biology, and Professor of Molecular Biophysics and Biochemistry at Yale University. He serves as Chair of the Department of Molecular Biophysics and Biochemistry and is an Investigator at the Howard Hughes Medical Institute. His research focuses on nucleic acid functions, including riboswitch discovery, RNA engineering, and molecular switch technology. Breaker earned his PhD in Biology/Biochemistry from Purdue University (1992) and BS in Biology/Chemistry from the University of Wisconsin-Stevens Point (1987).
Breaker’s research has identified over 30 riboswitch classes and pioneered the use of in vitro evolution for creating functional RNAs and deoxyribozymes. His work on riboswitches revealed their role in metabolite sensing and gene regulation, with applications in antibiotic development. He has co-founded two biotech companies, Archemix and BioRelix, and holds editorial roles at journals like RNA Biology and Cell Chemical Biology.
His awards include the National Academy of Sciences’ Molecular Biology Award, the Merck Award (ASBMB), and election to the National Academy of Sciences (2014) and American Academy of Arts and Sciences (2021). Breaker’s lab employs bioinformatics, genetics, and biochemistry to explore RNA’s functional potential across diverse bacterial species.
