Daniel L. Brinton

Daniel L. Brinton, PhD, MHA, MAR, is Associate Professor of Healthcare Leadership and Management at the Medical University of South Carolina, College of Health Professions. He specializes in advanced quantitative methods for health-services and observational research, leveraging large-scale electronic health records and administrative data to improve patient outcomes and inform policy.

Education:

• Doctor of Philosophy (PhD)
• Master of Health Administration (MHA)
• Master of Arts in Religion (MAR)

Research Interests:

Dr. Brinton’s work centers on missing-data methodologies that enable robust inference from real-world clinical datasets. He applies these techniques to pediatric health-services research, examining access, quality, and cost of care for asthma, Kawasaki disease, firearm injury, and autism spectrum disorder. A second major strand explores critical-care outcomes, using machine-learning and natural-language-processing to phenotype acute respiratory distress syndrome (ARDS) and optimize ventilator management. He also investigates orthopaedic surgery quality, opioid-prescribing patterns, and efficiency of global clinical trials.

Recent Research Trends:

Across 34 publications from 2018-2025, Brinton has increasingly integrated machine learning and big-data analytics to address clinical questions that were previously infeasible at scale. Studies range from predictive modeling of ARDS and neonatal acute kidney injury to economic evaluations of extended VTE prophylaxis and pediatric asthma adherence interventions.

Scientific Awards:

• No awards explicitly listed in the provided materials.

Advising & Grants:

While individual student names are not disclosed, Dr. Brinton mentors graduate students and junior investigators in the Department of Healthcare Leadership and Management. His research has been supported by federal and foundation grants focusing on comparative effectiveness, health economics, and informatics, although specific grant identifiers are not provided.

Labs & Teams:

Dr. Brinton collaborates with multidisciplinary teams at MUSC, including the College of Health Professions’ Healthcare Leadership and Management research group, critical-care investigators, pediatric specialists, and external partners utilizing national EHR networks such as the Pediatric Health Information System (PHIS).