Daniel Bondeson

Daniel Bondeson is an Assistant Professor at UMass Chan Medical School's Systems Biology department. His affiliations span multiple graduate programs, including Biochemistry and Molecular Biotechnology, Cancer Biology, and the MD/PhD Program.

Education:

• B.S. in Chemistry, University of Wisconsin, Stevens Point
• Ph.D. in Molecular Biophysics & Biochemistry, Yale University

Research Interests:

• Specializes in Targeted Protein Degradation using PROTAC technologies
• Investigates Phosphate Dysregulation in cancer pathogenesis
• Explores Protein Complexes like XPR1-KIDINS220 as therapeutic targets
• Conducts Genome-Scale CRISPR/CAS9 Screens for pediatric glioma dependencies
• Develops In Vivo Genetic Models using Drosophila
• Focuses on Cancer Epigenetics and chromatin-based therapies

Publication Trends:

• His 15 most recent articles (2025-2019) show consistent focus on PROTAC Design, Phosphate Homeostasis, and Cancer Targeting
• Key themes include Protein Degradation Mechanisms, BRAF Fusion Oncogenesis, and CRISPR Screening Applications

Networks:

• Research concepts include Proteolysis, Small Molecule Libraries, and Ubiquitin-Protein Ligases
• Collaborates with colleagues in Systems Biology and Physical Neighbors at UMass Chan