معرفی
Jun Yin is an Associate Professor at Georgia State University's College of Arts & Sciences specializing in protein engineering, ubiquitin pathways, and cell signaling. He earned his PhD from the University of California at Berkeley and completed postdoctoral training at Harvard Medical School. His research focuses on developing orthogonal ubiquitin transfer systems to identify substrates of E3 ubiquitin ligases involved in diseases including cancer and neurodegeneration.
His laboratory employs protein engineering techniques including phage display and yeast cell surface display to study ubiquitin-mediated protein degradation. Research interests include proteomic profiling of E3 ligase substrates, development of PROTAC therapeutics, and regulation of viral proteins through ubiquitination. Current projects investigate Parkin's role in SARS-CoV-2 infection and novel cancer therapies targeting Aurora kinases.
Yin's publication record demonstrates consistent innovation in chemical biology tools for ubiquitin research, with recent advances in PROTAC design, peptide activators of ubiquitin ligases, and methodology for studying linkage-specific ubiquitination. His work bridges fundamental biochemistry with therapeutic applications in oncology and virology.
