Dan Hampshire

Dr. Dan Hampshire is a Lecturer in Genetics at the Centre for Biomedicine, Hull York Medical School, University of Hull. He holds a BSc (Hons.) in Human Genetics and PhD in Molecular Medicine from the University of Leeds. His postdoctoral research at the University of Sheffield (12 years) investigated von Willebrand factor under a NIH Program Project Grant with international collaborators.

His research focuses on genetic factors influencing von Willebrand factor (VWF) plasma levels and their implications in bleeding/thrombosis. Key areas include:

• Transcriptional regulation of the VWF gene
• Impact of genetic variants on VWF biosynthesis/clearance
• Clinical outcomes of VWF variation in acute coronary syndromes
• Variant database curation for haemostasis disorders (ClinGen, EAHAD)

Analysis of his 15 most recent publications reveals consistent themes: VWF genetics (11 papers), variant databases (3), coagulation disorders (6), and diagnostic genomics (4). Methodologies span molecular biology, bioinformatics, and clinical haematology.

Awards:

• ISTH Young Investigator Award (2009, 2011)

Supervision:

• Current: Abigail Walne (PhD, VWF genetics), Hikmat Sulayman (MSc, endometriosis genetics)
• Former: Simon Webster (PhD), Ahmad Mufti (PhD)

Leadership roles: Editorial Board (Blood Coagulation & Fibrinolysis), ClinGen VWD Expert Panel Co-chair, EAHAD Steering Group.