معرفی
D. (Dick) de Zeeuw is a Professor at the Department of Clinical Pharmacy and Pharmacology, Faculty of Medical Sciences, University of Groningen. He focuses on diabetes-related kidney disease, cardiovascular pharmacology, and clinical trial design.
- Affiliation: University of Groningen, Faculty of Medical Sciences
- Role: Professor in Clinical Pharmacy and Pharmacology
His research targets chronic kidney disease (CKD) in diabetic patients, exploring:
- Mechanisms of kidney failure progression
- Pharmacotherapeutic interventions (SGLT2 inhibitors, RAAS blockers, aldosterone synthase inhibitors)
- Risk stratification through biomarkers (albuminuria, eGFR dynamics)
- Cardiorenal protective effects
- Racial/geographic variability in treatment responses
Recent studies include Phase I/II trials of BI 690517 (aldosterone synthase inhibitor) and CANPIONE trial analyzing canagliflozin's impact on pre-intervention eGFR slopes. Collaborative work spans multinational clinical meta-analyses.
Scientific contributions:
- Systematic reviews of ACE/ARB use in advanced CKD
- Development of prognostic imaging biomarkers for diabetic kidney disease (iBEAt protocol)
- Validation of biomarkers in PROVALID cohort
- Analysis of diuretic effects on fluid retention markers
۰مقاله منتشرشده
