معرفی
Dr. Cristina Lo Celso is a Professor in the Department of Life Sciences at Imperial College London, Faculty of Natural Sciences. She co-directs the Centre for Haematology & Stem Cell Biology and leads the Bone Marrow Dynamics Group. Her research focuses on understanding healthy and malignant hematopoiesis through advanced imaging techniques and interdisciplinary approaches. Dr. Lo Celso’s work integrates intravital microscopy, computational analysis, and mathematical modeling to study leukemia progression, bone marrow microenvironment interactions, and stress responses in hematopoietic stem cells.
Teaching responsibilities include the Stem Cells, Regeneration and Ageing (SCRA) course for Biochemistry/Biology undergraduates, immunology modules, and MSc programs in Applied Biosciences and Regenerative Medicine. She has affiliations with multiple networks, including the Imperial College Network of Excellence in Malaria, the Institute for Molecular Science and Engineering, and the Stem Cell Regenerative Medicine Network.
Her research explores how inflammation, infection, and cancer disrupt hematopoietic systems, with a focus on niche interactions and therapeutic strategies. Key areas include malaria-induced bone marrow remodeling, AML pathogenesis, and the role of bone marrow stroma in leukemia progression. She has pioneered intravital microscopy techniques to visualize stem cell behaviors in living organisms.
Dr. Lo Celso’s lab investigates niche heterogeneity, stem cell dormancy, and targeted therapies using MMP inhibitors and nanoparticle-based drug delivery systems. Her work bridges basic science with translational applications in regenerative medicine and oncology.
