معرفی
Clarissa Durie, Ph.D., is an Assistant Professor in the Department of Biochemistry at the University of Missouri School of Medicine. Her research focuses on bacterial protein secretion systems and membrane translocation mechanisms using cryo-electron microscopy and biochemical approaches.
Education:
- Ph.D., Chemistry, University of Alabama at Birmingham
- B.S., Chemistry, University of Alabama at Birmingham
- B.B.A, Marketing, College of William and Mary
Her interdisciplinary work combines structural biology, enzymology, and genetics to study how bacterial pathogens translocate virulence factors across membranes. Key areas include type IV secretion systems (T4SS), molecular motor regulation, and allosteric protein dynamics.
Recent publications highlight her expertise in cryo-EM structure determination of secretion systems (T4SS in Legionella and Helicobacter), mechanistic studies of AAA+ ATPases like Hsp104/ClpB, and explorations of allosteric regulation exceptions. She also investigates AI applications in cryo-EM data analysis.
Laboratory: Schweitzer 137 at the University of Missouri.
