Chun-Wei Chen

Chun-Wei Chen is an Assistant Professor at the Department of Systems Biology, City of Hope National Medical Center. His research focuses on epigenetic mechanisms in cancers, therapeutic target discovery using high-throughput genetic screens, and systems biology approaches to leukemia. He leads the Division of Epigenetics and Transcriptional Engineering.

• B.S., National Taiwan University (1996)
• M.S., Bioindustrial Chemistry, National Taiwan University (1998)
• Ph.D., Pathology, University of Rochester (2011)
• Postdoctoral Training, Children’s Hospital Boston/Harvard Medical School (2011-2012)

Dr. Chen specializes in high-throughput CRISPR screens coupled with next-generation sequencing to identify therapeutic targets in leukemia, particularly focusing on epigenetic dysregulation and signal transduction. His work has implications for FLT3 inhibition, metabolic reprogramming, and immune evasion in B-cell malignancies.

His recent publications highlight applications of CRISPR and epigenetic regulation in leukemia, with a trend toward synergistic therapies and RNA demethylation. Funding includes NIH R01, R37, R00 grants and support from the American Society of Hematology. He has no formal advisees listed.