معرفی
Dr. Chuanjie (Charles) Loh is a Research Group Leader at the Department of Chemical Biology, Max Planck Institute of Molecular Physiology in Dortmund, Germany. His work bridges organic synthesis and biochemical applications, focusing on biomimetic catalysis for carbohydrate-based molecular probes.
- Education: PhD (RWTH Aachen, summa cum laude), Postdoc (University of Toronto), Master (TUM/NUS Joint Programme), Bachelor (NUS, 1st Class Honors)
- Current Role: Group Leader since 2016
Research Interests:
- Biomimetic Synthesis: Developing catalytic glycosylation methodologies inspired by glycosyltransferase mechanisms, emphasizing hydrogen/halogen bonding and mechanistic-driven optimization.
- Phenotypic Screening: Exploring synthetic glycosides' biological roles in oncological pathways via chemical genetics.
Scientific Contributions include groundbreaking work on strain-release glycosylation and chalcogen/halogen bonding catalysis, with applications in Hedgehog signaling inhibition and stereoselective carbohydrate scaffolds.
Scientific Awards:
- Liebig Fellow (Chemical Industry Fund)
- DFG Postdoctoral Fellowship
- NUS Undergraduate Scholarship
- Multiple Book Prizes and Medals
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