معرفی
Dr. Christos Chinopoulos is a researcher at Semmelweis University, specializing in mitochondrial bioenergetics and oncometabolism. His work focuses on understanding how cancer cells rewire metabolic pathways through altered protein expression, particularly in mitochondrial enzymes, to develop cancer-specific therapeutic strategies.
- Institution: Semmelweis University
- Key Research: Mitochondrial metabolic theory of cancer, OXPHOS inhibition, glutaminolysis, mtSLP
His research integrates biochemical analysis of mitochondrial pathways with therapeutic targeting, including studies on:
- OXPHOS limitations in astrocytes and tumors
- Alternative ATP production mechanisms in hypoxia
- Effects of metabolic inhibitors on cancer cells
- Protein expression profiling via RPPA technology
Recent publications highlight mitochondrial adaptations in hypoxia, OXPHOS-independent ATP synthesis, and metabolic vulnerabilities in cancer cells. His work bridges fundamental mitochondrial physiology with translational cancer therapy.
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