Christopher J Destache

Christopher J. Destache is a Professor in the Department of Pharmacy Practice at Creighton University School of Pharmacy and Health Professions. He holds dual roles as a faculty member and infectious diseases specialist, with a focus on HIV/AIDS, nanomedicine, and antimicrobial stewardship. His academic career began at Creighton University, where he earned his PharmD in 1984, followed by a Family Medicine Research Fellowship. He transitioned to academia in 1993, becoming tenured in 1995.

Education

• PharmD, Creighton University (1984)

Research Interests

Dr. Destache’s research spans clinical infectious diseases, HIV pathogenesis, and nanotechnology applications in drug delivery. His work emphasizes nanoparticle-based therapies for HIV prevention and treatment, as well as optimizing antimicrobial stewardship programs to combat resistance.

Recent Research Themes

His publications highlight studies on HIV prophylaxis via nanoparticles, outcomes of patients with comorbidities during the COVID-19 pandemic, and novel antimicrobial agents against mycobacterial infections. Key contributions include the development of long-acting antiretroviral formulations and assessments of therapeutic efficacy in humanized mouse models.

Grants & Awards

Recipient of FCCP and BCIDP certifications. Leading antimicrobial stewardship initiatives at Creighton’s health systems, focusing on improving antibiotic use and reducing Clostridioides difficile readmissions.

Teaching & Mentorship

Precepts 4th-year pharmacy students in infectious diseases consultations, teaches in pharmacy and physician assistant programs, and mentors infectious diseases fellows. Active in interprofessional education and telemedicine-driven stewardship outreach to rural hospitals.

Labs & Teams

Based in the Department of Pharmacy Practice, collaborates with virology, nanomedicine, and clinical pharmacology teams. Involved in multi-institutional projects through the Nebraska Center for Virology and Creighton’s antimicrobial stewardship network.