معرفی
Christophe Zimmer is a Professor and Head of the Imaging and Modeling Unit at the Institut Pasteur, affiliated with the Department of Computational Biology. His research bridges experimental biophysics and computational modeling, focusing on the 3D spatial organization of genomes and high-resolution imaging of cellular processes, particularly in pathogens like HIV.
His research interests span biophysics, cell biology, computational biology, deep learning, super-resolution microscopy, genome architecture, and bioimage informatics. He develops and applies quantitative methods to understand how genome folding influences function and how pathogens manipulate host cells.
The recent publications highlight a strong trend in deep learning applications for biological imaging, including automated detection of heart defects from µCT scans and accelerating super-resolution microscopy. Other key themes include spatial transcriptomics, single-molecule RNA imaging (smFISH), 3D genome reconstruction (GRAAL), and software development for bioimage analysis such as ZOLA-3D and ANNA-PALM.
His scientific contributions are recognized through leadership in major projects like ERC-2024-SyG-AI4AMR and INCEPTION, though specific awards are not listed in the provided text.
Zimmer actively supervises PhD students and postdoctoral researchers, fostering a collaborative environment. His lab has received funding from various sources, including P2I and D2I research projects, often in collaboration with other leading scientists at the Institut Pasteur and international partners.
He leads the Imaging and Modeling Unit, a multidisciplinary team combining expertise in microscopy, informatics, biophysics, and cell biology, and collaborates closely with other experimental groups at the Institut Pasteur.
حوزههای پژوهشی
