جست‌وجوی استاد و پژوهشگر

Jennifer Rossمشاهده پروفایل

استاد

• Biophysics
• Soft Matter Physics
• Biological Condensed Matter Physics
• +۵ مورد دیگر

Jennifer Ross is a Professor of Physics and Associate Dean for Creativity, Scholarship, and Research at the College of Arts & Sciences of Syracuse University . As a biophysicist, she investigates how cells organize their interiors through self-assembly and active matter principles, focusing on the microtubule cytoskeleton and enzyme-driven systems using single-molecule imaging . Her research bridges fundamental physics with biological organization . Education: Ph.D. in Physics, University of California, Santa Barbara (2004) B.A. in Physics and Mathematics, Wellesley College (2000) Research Focus: Self-organization of cytoskeletal networks Active matter dynamics in biological systems Motor protein interactions and cargo transport Programming circadian materials via biomolecular systems Microtubule severing mechanisms Recent Article Trends: 2025 studies explore kinesin-driven cytoskeletal composites, urease-DNA origami engineering, and crosslinker-regulated network mechanics 2024-2023 work examines ionic strength effects on microtubules, programmable circadian materials, and motor-cargo dynamics Earlier studies analyze actin-microtubule composites, liquid crystal phase control, and severing enzyme mechanisms Scientific Awards: Fellow of the American Physical Society (APS) and American Association for the Advancement of Science (AAAS) Cottrell Scholar (2025) and STAR Award Margaret Oakley Dayhoff Award (Biophysical Society) Grants: Leads multiple NSF, Sloan Foundation, and Research Corporation grants for projects like "Energy and Entropy Sculpting" and "Explorations: SUPER-Tech SHIP" . Teaching: Offers courses in experimental physics, microscopy, and biophysics, including a globally adopted hands-on microscope-building curriculum. Lab: Heads the Bio-Active Matter Lab , studying how cells harness noisy systems for autonomous organization.

Omar A. Salehمشاهده پروفایل

استاد

• Biophysics
• Soft Matter Physics
• Polymer Physics
• +۵ مورد دیگر

Professor Omar A. Saleh is a distinguished physicist and materials scientist at the University of California, Santa Barbara, holding appointments in both the Materials and Physics Departments. Since summer 2023, he has served as Chair of the Materials Department and maintains a minority appointment in the Biomolecular Science and Engineering (BMSE) Program, where he previously served as Director from 2013-2017. His educational background includes a B.S. in Physics from MIT (1997) and a Ph.D. in Physics from Princeton (2003), supported by a Hertz Fellowship. Following postdoctoral work at École Normale Supérieure in Paris developing single-molecule techniques for motor protein/DNA studies, he joined UCSB in 2005. Saleh's research centers on fundamental principles of biomolecular behavior through experimental investigation of biopolymer elasticity and biomimetic organelles. His lab pioneers precision single-molecule stretching experiments to study entropic/energetic contributions in soft systems and creates life-like behaviors using reconstituted nucleic acid/protein assemblies. Key focus areas include DNA nanostar phase separation, liquid-liquid phase behavior, intrinsically disordered proteins, and non-equilibrium biomolecular systems. His publication trends reveal a strong emphasis on biomolecular condensates (2023-2025), with recurring themes in DNA nanotechnology, polyelectrolyte physics, and single-molecule mechanics. Recent work explores tension-mediated control of phase separation, transcriptional regulation of biomolecular liquids, and active matter principles in DNA systems. NSF CAREER Award (2008) Bessel Research Award from Alexander von Humboldt Society (2017) Fellow of the American Physical Society (2019) Saleh actively mentors graduate students and postdocs including Sam Wilken, Gabrielle Abraham, Anna Nguyen, and Aria Chaderjian, whose research spans DNA nanostar liquids, active droplets, and complex coacervation. His lab develops innovative instrumentation including high-speed magnetic tweezers and GPU-based tracking systems, supported by grants such as NSF/MCB-BSF: Direct force measurements of intrinsically disordered proteins. The Saleh Group operates at BioE 3006, focusing on creating quantitative models of biological function through physical reconstitution.

Sriram Subramaniamمشاهده پروفایل

استاد

• cryo-electron microscopy
• structural biology
• drug-design
• +۴ مورد دیگر

Sriram Subramaniam is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia (UBC) and holds the Gobind Khorana Canada Excellence Research Chair in Precision Cancer Drug Design. His research leverages cryo-electron microscopy (cryo-EM) to advance structural biology and drug design, focusing on protein dynamics and therapeutic target identification. Education: PhD in Physical Chemistry (1987) from Stanford University; MSc in Chemistry (1981) from Indian Institute of Technology, Kanpur. Subramaniam's interdisciplinary work combines cryo-EM with computational tools and molecular biology to study protein structures at atomic resolution. His lab has pioneered cryo-EM applications in precision medicine, including mapping small molecule drugs on patient-specific cancer mutants. Recent publications (2024-2022) highlight his contributions to understanding SARS-CoV-2 immune evasion, structural mechanisms of ATPases, and AI integration in structural biology. His research spans viral entry mechanisms, CRISPR systems, and neurodegenerative disease pathways. Scientific Awards: Gobind Khorana Canada Excellence Research Chair NIH Director’s Award for Scientific Excellence Fellow of the Biophysical Society Breakthrough Prize nomination Based at the Djavad Mowafaghian Center for Brain Health, Subramaniam leads the Program in Cryo-EM Guided Drug Design, contributing to over 177 peer-reviewed publications with a career h-index of 58 and citations exceeding 12,340.

Shasha Chongمشاهده پروفایل

استادیار

• Transcriptional Regulation
• Intrinsically Disordered Proteins
• Single-Molecule Biophysics
• +۴ مورد دیگر

Shasha Chong is an Assistant Professor of Chemistry at the California Institute of Technology and a Ronald and JoAnne Willens Scholar. She earned her B.S. from the University of Science & Technology of China (2008) and Ph.D. from Harvard University (2014). Her research bridges chemistry, physics, and biology to investigate the molecular mechanisms of cellular processes, focusing on intrinsically disordered regions (IDRs) in transcription proteins. Research Focus: IDRs in transcriptional regulation, cancer biology, liquid-liquid phase separation, and single-molecule imaging techniques. Grants & Awards: CCE Innovation Award (2024), ALSF Innovation Grant, Mallinckrodt Research Grant, Margaret E. Early Medical Research Trust Grant. Collaborations: Caltech-City of Hope Biomedical Research Initiative Grant (2025). Teaching: Co-instructor for courses like Biochemistry Laboratory (Ch 11) and Advanced Topics in Biochemistry (BMB/Bi/Ch 174). Labs & Teams: Leads the Chong Laboratory at Caltech, focusing on interdisciplinary approaches combining single-molecule imaging, genome editing, and bioinformatics.

Vadim Cherezovمشاهده پروفایل

استاد

• Membrane Protein Structure and Function
• G Protein-Coupled Receptors (GPCRs)
• Lipid-Protein Interactions
• +۳ مورد دیگر

Vadim Cherezov, the Ester Dornsife Chair in Biological Sciences and Professor at the University of Southern California (USC), leads groundbreaking research in membrane protein structure and function. Affiliated with the Bridge Institute, Department of Chemistry, and Michelson Center for Convergent Bioscience, his work focuses on GPCRs, ion channels, and transporters—critical targets for drug discovery. His team leverages advanced techniques like Lipidic Cubic Phase (LCP) and Serial Femtosecond Crystallography (SFX) at XFEL facilities to solve high-resolution structures under physiological conditions. Institutional Affiliations: Bridge Institute, USC Michelson Center, Department of Chemistry, Department of Pharmacology and Pharmaceutical Sciences. Key Collaborations: Katritch Lab, Kuhn Lab, NIH, European XFEL. His research explores the role of lipids in modulating GPCR function, addressing diseases like Alzheimer’s, diabetes, and cancer. By solving the structure of the A 2A adenosine receptor via sulfur SAD phasing at XFEL, Cherezov’s lab demonstrated de novo phasing without heavy atoms. This breakthrough enables structural studies of previously intractable membrane proteins. Scientific Awards & Grants: NIH R01 GM108635, U54 GM094618, U54 GM094599, R01 GM095583 Science Signaling Breakthroughs of the Year (2014) Cherezov mentors a dynamic team, including postdocs (e.g., Dong-Gyun Kim), graduate students (e.g., Behnaz Davoudinasab), and alumni (e.g., Benjamin Stauch at Eli Lilly, Nairie Michaelian at Genentech). His lab’s publications span Nature , Science , and Cell , with recent work on Science Advances (2025) addressing ABEL-FRET for GPCR dynamics.

Christoph Schmidtمشاهده پروفایل

استاد

• Biophysics
• Cell Mechanics
• Microrheology
• +۵ مورد دیگر

Christoph F. Schmidt is the Hertha Sponer Distinguished Professor of Physics at Duke University with cross-appointments in the Thomas Lord Department of Mechanical Engineering and Materials Science, Biology, and Biomedical Engineering. He serves as Co-Director of the Duke Materials Initiative and leads an active research program at the intersection of physics and biology. His educational background includes a D.R. from the Technical University of Munich (Germany) in 1988. Schmidt has established himself as a leading researcher in biophysics through decades of innovative work. Professor Schmidt's research spans multiple scales of biological organization, from single molecules to whole organisms. His lab investigates cellular mechanics using advanced techniques including optical trapping, atomic force microscopy, and microrheology. A significant innovation from his group involves single-walled carbon nanotubes for high-bandwidth intracellular tracking. Current research focuses on cardiomyocyte mechanics, Drosophila tissue dynamics, and computational analysis of complex biological systems. His work on motor proteins like Eg5 and ncd has provided fundamental insights into cellular division mechanics. His recent publications (2021-2025) demonstrate increasing integration of computational approaches with experimental biophysics, particularly in analyzing cardiac tissue mechanics and Drosophila sensory systems. The work shows progression from fundamental biophysical measurements toward applications in understanding disease mechanisms and biological function. Professor Schmidt teaches several courses including PHYSICS 995 (Graduate Training Internship), PHYSICS 493 (Research Independent Study), PHYSICS 415 (Biophysics II), PHYSICS 174 (Introduction to Frontiers of Biophysics), and BIOLOGY 425 (Biophysics II). He has successfully mentored numerous graduate students to completion, including recent PhD graduates Dr. Mingru Li and Dr. Xiaoxuan Jian. The Schmidt Lab, part of Duke's Physics Department and the Duke Soft Matter Center, maintains state-of-the-art equipment for optical trapping, atomic force microscopy, and advanced light microscopy. The lab participates in the Triangle Soft Matter Workshop, fostering collaborations with researchers from Duke, UNC Chapel Hill, and NC State University. Current research directions include mechanical responses of suspended cells, tracking non-equilibrium cellular fluctuations, nuclear mechanics, and bacterial membrane mechanics under turgor pressure.

Jered Haunمشاهده پروفایل

دانشیار

• Biomedical Engineering
• Molecular Medicine
• Nanotechnology
• +۴ مورد دیگر

Jered Haun is an Associate Professor at the Samueli School of Engineering , University of California, Irvine , with joint appointments in Biomedical Engineering , Chemical and Biomolecular Engineering , and Materials Science and Engineering . Based in 3107 Natural Sciences II , his research focuses on developing nanoengineering and molecular medicine technologies to improve disease diagnosis and treatment. Email: jered.haun@uci.edu Phone: (949) 824-1243 Research Interests include: Nanomaterial Probes for molecular profiling and disease detection Microfabricated Platforms for cell analysis and tissue processing Targeted Delivery Carriers that interact with unique disease molecules Technologies employed in his lab encompass: Fluorescence imaging and MRI enhancements Bioorthogonal chemistry and nanosensor development Micro-NMR for tumor analysis Quantum dot-based detection systems Awards include: NIH National Cancer Institute's Innovative Molecular Analysis Technologies Funding The Haun Laboratory actively recruits graduate and undergraduate students for projects related to nanoengineering, molecular medicine, and microfluidic device development.

Mark Wallaceمشاهده پروفایل

استاد

• Membrane Biology
• Biophysics
• Optical Microscopy
• +۳ مورد دیگر

Mark Wallace is a Professor of Chemistry at King's College London, affiliated with the Department of Chemistry and the Faculty of Natural, Mathematical & Engineering Sciences. He holds a Royal Society University Research Fellowship (2005–2016) and has been a lecturer at Oxford University before joining King's in 2016. His research focuses on membrane protein function and artificial membrane mimics, combining optical microscopy and nanotechnology. He earned a PhD from the University of Cambridge (2002) and postdoctoral training at Stanford University and the National Institute for Medical Research. Key research interests include membrane protein dynamics, lipid bilayer engineering, and single-molecule imaging. He has pioneered techniques like droplet interface bilayers and interferometric scattering microscopy. His work has led to patents and applications in molecular sensing and medical research. Awards include the 2002 Gregorio Weber Prize and the 2015 RSC Norman Heatley Award. He is actively involved in public outreach, including video podcasts and educational competitions. Recent publications emphasize artificial ion channels, nanoparticle formation monitoring, and mitochondrial protein dynamics. His lab collaborates with institutions like the London Centre for Nanotechnology and the Rosalind Franklin Institute. Over 30 students and researchers have been mentored, with active grants from EPSRC, Wellcome Trust, and BBSRC.

• Biophysics
• Membrane Proteins
• Structural Biology
• +۳ مورد دیگر

Dr. Lukas Frey is a Researcher at ETH Zurich, affiliated with the Chair of Physical Chemistry and the Institute of Molecular Physical Sciences (IMPS). His work focuses on biophysical studies of membrane proteins, lipid dynamics, and protein aggregation mechanisms. Key research areas include structural biology of ion channels, NMR spectroscopy of membrane proteins in nanodiscs, and the role of lipid environments in modulating protein dynamics. Frey employs advanced techniques like mass photometry and solid-state NMR to investigate molecular mechanisms in biological systems. His recent studies address amyloid fibril formation, pH-dependent α-synuclein polymorphism, and cholesterol-mediated modulation of membrane protein behavior. Based at the HCI F 228 facility in Zurich, Frey collaborates on projects involving lipid bilayer environments, ion channel function, and the structural basis of protein aggregation. His email is lukas.frey@phys.chem.ethz.ch, and he holds an ORCID identifier 0000-0002-1052-1104. Research contributions span from fundamental biophysical insights to methodological advancements in membrane protein analysis.

Matthew Lakinمشاهده پروفایل

دانشیار

• Molecular Computing
• DNA Nanotechnology
• Synthetic Biology
• +۷ مورد دیگر

Matthew Lakin is an Associate Professor with tenure in the Department of Computer Science at the University of New Mexico, with a courtesy appointment in the Department of Chemical & Biological Engineering. He is affiliated with the UNM Center for Biomedical Engineering and the School of Engineering, and collaborates extensively with the UNM Health Sciences Center and external institutions. Education: Ph.D., Computer Science, University of Cambridge, 2010 M.A. (Cantab), University of Cambridge, 2009 B.A. (Hons), Computer Science, University of Cambridge, 2005 Dr. Lakin's research focuses on molecular computing, DNA nanotechnology, synthetic biology, and formal verification of biomolecular circuits. He develops computational models and experimental systems for programmable biological devices, especially using heterochiral DNA to enhance stability in living cells. His work spans software tools for biodesign and experimental validation in mammalian systems, with applications in nanomedicine and biosensing. The recent publications highlight a strong trend in engineering robust, intelligent biomolecular systems. His work integrates machine learning concepts into chemical reaction networks, advances geometric modeling of DNA systems, and pioneers L-DNA-based circuits for intracellular applications. The research spans theoretical foundations, software tools, and wet-lab experimentation, emphasizing interdisciplinary innovation. Scientific Awards: Presidential Early Career Award for Scientists and Engineers (PECASE), 2025 NSF CAREER Award, 2021 UNM School of Engineering Junior Faculty Research Excellence Award, 2021 Multiple student awards under his mentorship, including the Outstanding Graduate Student Award and DNA28 Best Student Presentation recognition Dr. Lakin has advised numerous graduate and undergraduate students, including Ph.D. graduates in Biomedical Engineering and Computer Science. He leads major funded projects such as the NSF CAREER grant on heterochiral molecular computing, an EPSCoR Research Fellowship, and a $3M NSF grant on heavy metal biosensing in collaboration with Native American communities. He is also PI on multiple NSF grants related to synthetic cells and nucleic acid technologies. He directs the Lakin Lab for Programmable Biology, which operates within the Department of Computer Science and collaborates with Chemical & Biological Engineering and the Center for Biomedical Engineering. The lab emphasizes both computational modeling and experimental molecular biology, and runs an NSF-funded biotechnology summer camp in partnership with ¡Explora! science museum to strengthen STEM education in New Mexico.

Daniel Roxburyمشاهده پروفایل

دانشیار

• Nanoscience
• Carbon Nanotubes
• Nanomaterials
• +۴ مورد دیگر

Dr. Daniel Roxbury is an Associate Professor and Graduate Director at the Department of Chemical, Biomolecular and Materials Engineering within the University of Rhode Island's College of Engineering. With expertise in nanoscience and carbon nanomaterials, his research focuses on nano-bio interactions, developing functionalized nanotubes for biomedical applications and environmental monitoring through his NanoBio Engineering Laboratory. His work spans multiple disciplines including: Biomedical nanosensors Smart wearable biomaterials Targeted drug delivery systems Environmental nanotechnology Single-molecule imaging Nanotoxicology Recent publications emphasize machine learning-enhanced spectral analysis, coral reef conservation nanotechnology, and wearable stress monitoring textiles. His 2024 ACS Nano study introduces AI-driven macrophage phenotyping, while 2023 Nature Nanotechnology work explores coral reef restoration strategies using nanomaterials. Awarded the 2019 NSF CAREER grant for cellular nanometrology, he leads multiple NIH-funded projects including: $820,000 NSF CAREER: Spectral Imaging for Sub-Cellular Nanometrology $140,000 Miriam Hospital COBRE: Cortisol Detection Textiles $700,000 NSF EAGER: Multiplexed Wound Biomarker Detection His laboratory houses state-of-the-art equipment including: Near Infrared Hyperspectral Microscope Custom NIR Fluorescence Spectrometer Jasco UV/VIS/NIR Spectrophotometer Biosafety Cabinet Cell Culture Incubator Cryo-Storage System

• Biophysical Immunology
• Mechanobiology
• Microscopy Technology
• +۳ مورد دیگر

Marco Fritzsche is a Professor of Biophysical Immunology at the University of Oxford. He serves as the Scientific Director of the Oxford-ZEISS Centre of Excellence and leads the Biophysical Immunology Laboratory (www.bpi-oxford.com), which operates at the intersection of biophysics and immunology. BSc in Mathematics (2003–2006), University of Saarbrücken BSc in Physics (2003–2006), University of Saarbrücken MSc in Theoretical Physics (2006–2008), University of Saarbrücken PhD in Experimental Physics and Biology (2008–2012), University College London His research focuses on biophysical and mechanobiological mechanisms governing immune responses in health and disease. The BPI Laboratory develops advanced microscopy technologies to study these processes, integrating theoretical physics with experimental immunology. Recent publications highlight his work in quantitative imaging of biomolecular organization , traction force microscopy for immune cell dynamics, and trans-synaptic vesicle analysis in T-cell interactions. His studies bridge disciplines like biophysics, immunology, and cell mechanics. Rosalind Franklin Kennedy Trust Research Fellow The BPI Laboratory collaborates with institutions such as the Howard Hughes Medical Institute Janelia Farm and the Rosalind Franklin Institute . His roles include leadership in the Oxford-ZEISS Centre of Excellence and contributions to cutting-edge immunology research.

Kathrin Langمشاهده پروفایل

استاد

• Chemical Biology
• Protein Engineering
• Genetic Code Expansion
• +۳ مورد دیگر

Kathrin Lang is a Full Professor at the Department of Chemistry and Applied Biosciences, ETH Zurich, and Head of the Organic Chemistry Laboratory. Her research focuses on chemical biology, particularly the development of tools for genetic code expansion to incorporate non-canonical amino acids into proteins and advance bioorthogonal chemistries for studying biological processes. Keywords: Genetic Code Expansion, Bioorthogonal Chemistry, Protein Engineering, Ubiquitylation Networks, Post-Translational Modifications. Lang’s work emphasizes proximity-triggered crosslinking reactions, bioorthogonal labeling, and in vivo chemistries to address challenges in protein interaction mapping and structural elucidation. Her group’s recent publications highlight methodologies for dual protein labeling, deciphering ubiquitin code, and enhancing cycloaddition reactivity. Current projects include exploring cyclopropene-fused dibenzocyclooctynes for improved labeling and investigating methylated lysine as a conformational regulator in Hsp90. Funding sources include the ERC (Ubl-tool), DFG (SFB1035, SPP1926), and ETH Zurich. She contributes to education through courses like Genetic Code Expansion for Studying Posttranslational Modifications and Chemical Biology and Synthetic Biochemistry . Collaborative efforts span structural biology, microbiology, and synthetic biochemistry, with applications in ubiquitin research and cellular imaging.

Alex S Clarkمشاهده پروفایل

دانشیار

• Quantum Photonics
• Nanophotonics
• Quantum Technology
• +۴ مورد دیگر

Dr. Alex S Clark is an Associate Professor in Quantum Technologies at the University of Bristol's School of Physics, where he serves as a Senior Lecturer and Royal Society University Research Fellow. He is a key member of the Quantum Engineering Technology Labs (QETLabs) and leads the Interfaces Work Package in the EPSRC Programme Grant 'Quantum Science with Ultracold Molecules (QSUM).' Additionally, he holds a Visiting Academic position at Imperial College London and serves as Honorary Secretary for the QQQ Group at the Institute of Physics. His research focuses on Solid State Quantum Nanophotonics, exploring the use of atoms, molecules, and solid state defects to develop quantum technologies. Dr. Clark's work spans quantum imaging, quantum sensing, and quantum information processing, with particular emphasis on creating on-demand photon sources, quantum memories, photonic quantum gates, and hybrid interfaces to link disparate quantum systems. His research integrates experimental and theoretical approaches across quantum photonics, nanophotonics, and quantum technology. Analysis of his recent publications reveals a strong trend toward practical quantum applications, particularly in quantum sensing and imaging using undetected light. His work demonstrates increasing focus on real-world applications including methane sensing, medical diagnostics, and environmental monitoring, while maintaining fundamental research in quantum optics and nanophotonics. The interdisciplinary nature of his research bridges physics, engineering, and materials science. Among his notable achievements is the prestigious Royal Society University Research Fellowship, recognizing his significant contributions to quantum technology research. His work has resulted in numerous publications and patents in quantum photonics and related fields. Dr. Clark leads multiple major research initiatives, including the Quantum Positioning, Navigation, and Timing Hub (2024-2029) and the Integrated Quantum Networks project. His research has secured substantial funding through EPSRC grants and other sources, supporting a vibrant research group focused on advancing quantum technologies from fundamental principles to practical applications. Within the Quantum Engineering Technology Labs (QETLabs), Dr. Clark's research group works at the intersection of quantum optics, nanophotonics, and quantum information science. His team develops novel photonic platforms for quantum applications, with particular expertise in quantum imaging with undetected photons, quantum sensing, and integrated quantum photonics.

• Free-Electron Lasers
• Ultrafast X-ray Spectroscopy
• Nanoparticle Dynamics
• +۳ مورد دیگر

Christoph Bostedt holds dual appointments as a Professor of Physical Chemistry at the Ecole Polytechnique Fédérale de Lausanne (EPFL) and as Head of the Laboratory for Synchrotron Radiation and Femtochemistry (LSF) at the Paul Scherrer Institut (PSI). He leads strategic operations for the LSF, managing five research groups and overseeing four beamlines at the Swiss Light Source and the Alvra Endstation at SwissFEL. His research focuses on ultrafast x-ray science, including single-shot imaging, non-linear x-ray spectroscopy, and femtosecond pump-probe techniques. He collaborates globally on initiatives like the Athos project, aiming to advance ultrafast x-ray technologies. Bostedt has over 150 publications and is a Fellow of the American Physical Society, recipient of the Röntgen Prize. Education: Ph.D. from the University of Hamburg with research at Lawrence Livermore and Berkeley National Laboratories. Prior roles include leadership at Argonne National Laboratory and SLAC National Accelerator Laboratory. Research Interests: Single-particle imaging and coherent diffraction X-ray free-electron laser applications Ultrafast dynamics in nanoparticles and molecular systems Non-linear x-ray spectroscopy Time-resolved x-ray pump-probe methods Awards: Fellow of the American Physical Society Röntgen Prize (University of Giessen) Labs & Projects: Spearheads the Athos beamline project at SwissFEL, developing the Maloja endstation for ultrafast x-ray studies. Oversees the Laboratory for Femtochemistry and collaborates on advanced imaging techniques for nanoscale science.