Cheryl Keller

Cheryl Keller is a Research Professor in the Department of Biochemistry and Molecular Biology at Pennsylvania State University, and Director of the Genomics Research Incubator. Her research focuses on genomics, epigenetics, and gene regulation, particularly in hematological contexts such as fetal hemoglobin regulation and leukemia pathogenesis.

Her work integrates CRISPR technologies, chromatin structure analysis, and systems biology approaches to explore transcriptional networks and chromosomal architecture. Key areas include understanding mechanisms underlying erythroid differentiation, fetal hemoglobin expression, and the role of transcription factors like BCL11A and YY1.

Keller collaborates with the Huck Institutes of the Life Sciences and leads initiatives to expand genomic assay capabilities through the Genomics Research Incubator. Her studies bridge basic science and translational medicine, with implications for blood disorders like sickle cell disease.