Cheng Lin

Cheng Lin is a Research Professor at the Department of Biochemistry, Boston University. Their work focuses on advanced mass spectrometry techniques for glycomics and proteomics research, particularly using electron activated dissociation methods for glycan characterization.

• B.Sc., Peking University, Beijing, China
• Ph.D., Cornell University, Ithaca, NY

Research interests include:

• Development of integrated analytical and bioinformatics approaches for de novo glycan sequencing
• Application of EED and NETD fragmentation techniques
• Combining ion mobility spectrometry with mass spectrometry for complex glycan mixtures
• Theoretical studies on glycan dissociation mechanisms
• Collaborative software development for spectral interpretation

Key publication trends show expertise in:

• Trapped ion mobility spectrometry (TIMS)
• Hydrophilic interaction liquid chromatography (HILIC)
• De novo glycan topology reconstruction
• Characterization of isomeric and sulfated glycans
• Algorithm development for mass spectrometry data
• Instrumentation optimization for high-throughput analysis

Notable laboratory members:

• Nadia Cherkassky - Postdoctoral Associate
• Yongting Chen - Undergraduate Student