Charles Matouk

Dr. Charles Matouk is an Associate Professor of Neurosurgery and Radiology & Biomedical Imaging at Yale University, where he serves as Vice Chair of Clinical Affairs, Chief of Neurovascular Surgery, and Director of the Neurovascular/Endovascular Fellowship. His clinical expertise spans brain aneurysms, vascular malformations, carotid occlusive disease, acute stroke syndromes, and adult-onset hydrocephalus.

• MD: University of Calgary (1999)
• BS: McGill University (1996)
• Residency: University of Toronto (2009)
• Fellowship: University of Toronto (2011)

Dr. Matouk’s research integrates clinical trials and advanced neuroimaging. He leads trials like ASTROH (heparin therapy for SAH), NEWTON (aneurysm treatment), and CREST-2 (carotid revascularization). His translational work explores imaging to prioritize high-risk aneurysms and vascular malformations.

His 2025 publications focus on thrombectomy outcomes, stroke risk factors, minimally invasive surgery for hemorrhage, and neurovascular device development. Collaborators include Kevin Sheth, Nils Petersen, and Guido Falcone.

• McLaughlin Centre for Molecular Medicine Medical Scientist Training Fellowship
• CIHR Research Fellowship
• AANS/NREF Research Fellowship

Dr. Matouk emphasizes patient-centered care, using radiology images and procedural sketches to aid decision-making. He is board-certified by the Royal College of Physicians and Surgeons of Canada and leads the Hereditary Hemorrhagic Telangiectasia (HHT) Program and Normal Pressure Hydrocephalus Program at Yale Medicine.