Charles Dye

Charles Dye, MD is a Professor in the Department of Medicine, Division of Gastroenterology and Hepatology, specializing in interventional endoscopy for gastrointestinal diseases with emphasis on pancreatic and esophageal pathologies.

His research focuses on:

• EUS-guided ablation of premalignant pancreatic cysts (NIH-funded CHARM II trial co-investigator)
• Endoscopic Mucosal Resection (EMR) and cryotherapy
• Innovative endoscopic technologies including the Chimera Project with Penn State Bioengineering
• Advanced therapies for Barrett's esophagus and esophageal disruptions

Recent publications (2017-2024) demonstrate leadership in randomized trials for colorectal polyp resection, pancreatic cyst ablation, and novel endoscopic techniques, establishing minimally invasive approaches as standards in gastrointestinal oncology.

Dr. Dye actively collaborates on medical device development through the Chimera Project, creating EUS-guided systems combining radiofrequency ablation and targeted radiation for abdominal tumors, while contributing to UN Sustainable Development Goals through cancer prevention research.