معرفی
Changchun Chen is an Associate Professor at the Department of Molecular Biology, Umeå University, affiliated with the Wallenberg Centre for Molecular Medicine (UCMM). His research focuses on oxygen sensation mechanisms in Caenorhabditis elegans, combining genetic screens, biochemistry, calcium imaging, and optogenetics to unravel molecular and neural circuit adaptations to extreme conditions.
- Wallenberg Molecular Medicine Fellow (2018)
- ERC Starting Grant recipient (2018)
- Florman Prize from the Royal Swedish Academy of Sciences (2025)
Chen’s work explores the neuronal basis of behavioral and physiological responses to hypoxia/anoxia, with implications for human pathogenesis. His lab investigates how ROS, cGMP, and IL-17 signaling modulate stress tolerance and survival strategies.
Recent publications highlight his contributions to understanding GPCR signaling, tRNA modifications, and IL-17’s role in longevity. His studies often utilize C. elegans as a model for neurobiological and molecular disease mechanisms.
- ERC Starting Grant (€1.5 million) for molecular medicine research
- Florman Prize (2025) for breakthroughs in molecular biology
The Changchun Chen Lab is part of Umeå University’s Department of Molecular Biology and collaborates with the Wallenberg Centre for Molecular Medicine. Funding sources include the Knut and Alice Wallenberg Foundation, European Research Council, and Swedish Research Council.
