Cesare Orlandi

Cesare Orlandi is an Associate Professor at the Department of Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry. His research focuses on orphan G protein coupled receptors (GPCRs) in brain and visual systems, exploring their roles in physiology and disease.

• University of Rochester School of Medicine and Dentistry
• NIH T32 Training Grant in Cellular, Biochemical & Molecular Sciences

His lab develops innovative tools like the GzESTY assay for GPCR deorphanization, applying proteomics, biochemistry, and pharmacology to uncover therapeutic targets. Recent studies highlight GPRC5B's role in macrophage function and GPR158's impact on stress-induced depression.

Current work explores cAMP dynamics and synaptic organization through collaborations, including the lab of Dr. John D. Lueck. The lab trains graduate students and postdoctoral fellows in advanced methodologies.