معرفی
Caroline Jolley is a Reader in Respiratory Medicine & Physiology at King's College London, where she works within the Centre for Human & Applied Physiological Sciences. Her research focuses on understanding the physiological mechanisms underlying breathlessness and respiratory conditions, with particular expertise in respiratory muscle function, dyspnea assessment, and chronic cough. Dr. Jolley is an active contributor to the PHOSP-COVID study, investigating long-term respiratory consequences following COVID-19 hospitalization.
Dr. Jolley's primary research interests include respiratory physiology, dyspnea mechanisms, chronic cough, and the pathophysiology of breathlessness in various conditions including COPD, post-COVID syndrome, and chronic cough disorders. Her work combines clinical research with physiological measurements to better understand how respiratory symptoms relate to underlying physiological changes. She has made significant contributions to understanding neural respiratory drive, electromyography applications in respiratory assessment, and the development of novel non-invasive indices for respiratory muscle strength. Her research often bridges basic physiological principles with clinical applications to improve patient care.
Her recent publications demonstrate a strong focus on post-COVID respiratory complications, with multiple high-impact studies examining dyspnea, lung function, and recovery trajectories. She has also made important contributions to understanding chronic cough mechanisms, particularly related to neuropathic causes and genetic factors such as RFC1 gene expansions. Her work frequently involves large multicenter collaborations, with publications in top journals including The Lancet Respiratory Medicine and Current Opinion in Supportive and Palliative Care.
Dr. Jolley has secured funding from major organizations including Asthma and Lung UK, BMA Foundation, EPSRC, and NIHR. Current projects include investigating physiological mechanisms of breathlessness in long-COVID, developing novel non-invasive indices of respiratory muscle strength for investigation of respiratory failure, and exploring social prescribing interventions for respiratory conditions such as the SPLASH project for bronchiectasis. She is also involved in the SPARiA project developing Symmetric Projection Attractor Reconstruction as a novel assessment tool in asthma.
As an active researcher with over 4,400 citations, Dr. Jolley contributes significantly to the respiratory research community through her leadership in multiple projects and collaborations. Her work has practical implications for improving assessment and management of breathlessness and chronic cough, with potential applications across various respiratory conditions.
