
معرفی
Carl Caleman is a Research Fellow at the Center for Free-Electron Laser Science (CFEL) and holds an affiliation with the University of Uppsala, Department of Physics and Astronomy. He is a key member of the Coherent Imaging Team, focusing on the theoretical and computational aspects of X-ray free-electron laser (XFEL) interactions with matter. His work bridges physics, chemistry, and biology, with a strong emphasis on ultrafast dynamics and radiation effects in biomolecular systems.
His research interests encompass a wide range of topics, including
- X-ray Free-Electron Lasers (XFELs)
- Molecular Dynamics Simulations
- Radiation Damage in Biomolecules
- Single Particle Imaging
- Ultrafast Ionization and Fragmentation Dynamics
- Protein and Viral Capsid Stability
- Surface Science of Liquids and Ionic Liquids
- Charge Transfer Processes
The analysis of his recent publications (2023–2025) reveals a consistent focus on using hybrid computational methods—combining collisional-radiative models with molecular dynamics—to study radiation damage, molecular explosions, and structural changes in proteins, viruses, and aqueous systems exposed to XFELs. His work is pivotal for advancing the field of serial femtosecond crystallography and single-particle imaging, where understanding and mitigating radiation damage is critical. He frequently publishes in high-impact journals such as Nature Communications, Physical Review Letters, and Physical Chemistry Chemical Physics, often as a corresponding author, indicating his leadership in collaborative research projects.
Carl Caleman is actively involved in a large network of international collaborations, working with scientists from DESY, XFEL.EU, CSSB, EMBL, and other institutions. His research is supported by access to major XFEL facilities and high-performance computing resources. He advises and mentors junior researchers and students within his team, fostering the next generation of scientists in the field of ultrafast science. His work has significant implications for structural biology, materials science, and radiation therapy.
He is associated with the following laboratories and research teams:
- Coherent Imaging Team, Center for Free-Electron Laser Science (CFEL)
- Collaborative Research Center on Structural Dynamics of Biomolecular Machines (CSSB)
- DESY (Deutsches Elektronen-Synchrotron)
- European XFEL
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