Carl Caleman

Carl Caleman is a Professor at the Department of Physics and Astronomy at Uppsala University, specializing in X-ray physics and molecular dynamics. His research focuses on the structural dynamics of biomolecules and materials under ultrafast X-ray laser irradiation, including radiation damage mechanisms, protein crystallography, and the development of computational models for X-ray-matter interactions. He leads the Molecular Dynamics and Structure group at the Division for Molecular and Condensed Matter Physics.

Key research areas include:

• Ultrafast X-ray laser-induced phenomena in biomolecules
• Simulations of radiation damage in protein crystals
• Development of tools like FreeDam for predicting radiation damage in femtosecond crystallography
• Structural studies of water and ionic liquids at interfaces

Recent work explores anisotropic ice melting, viral capsid stability, and novel imaging techniques like correlated X-ray fluorescence imaging. His publications span high-impact journals such as Nature, Science, and Proceedings of the National Academy of Sciences.

Notable contributions include the Diffraction Before Destruction concept for single-particle imaging and advancements in femtosecond crystallography methods for studying biomolecular dynamics.