C. Anthony Hunt

C. Anthony Hunt is a Professor at the University of California San Francisco (UCSF), affiliated with the School of Pharmacy and the Department of Bioengineering and Therapeutic Sciences. He also maintains external affiliations with F. Hoffmann-La Roche Ltd. and the Office of Clinical Pharmacology (OCP), U.S. Food and Drug Administration.

• Education:
  • BSc in Applied Biology, Georgia Institute of Technology
  • BSc in Chemistry, Georgia Institute of Technology
  • PhD in Pharmaceutical Sciences, University of Florida

Research Interests focus on theoretical systems pharmacology, multiscale modeling, and computational biology to understand causal mechanisms linking molecular changes to organism-level phenotypes. His work emphasizes personalized medicine, biomedical informatics, and therapeutic bioengineering, particularly in drug development and regulatory sciences.

Scientific Contributions include developing synthetic modeling methods for mechanistic hypothesis testing in drug metabolism, liver injury, and epithelial cell dynamics. He has published extensively in PLoS Computational Biology, Journal of Pharmacology and Experimental Therapeutics, and BMC Systems Biology, with over 25 years of continuous NIH funding to his research group.

• Major Awards:
  • American Association for the Advancement of Science (1984)
  • Highest Honors in Chemistry, Georgia Institute of Technology (1970)

Laboratory Work involves creating biomimetic computational models of hepatocytes, epithelial cells, and drug transport systems. His team has developed in silico livers, virtual transwell devices, and agent-based frameworks for studying cellular interactions and drug disposition across multiple scales.