معرفی
Bruce G. Allen is a Professor in the Department of Biochemistry and Molecular Medicine at Université de Montréal's Faculty of Medicine and researcher at the Montreal Heart Institute. His laboratory investigates nuclear G-protein coupled receptor signaling in cardiac cells, p38 MAP kinase pathways in heart hypertrophy, and molecular mechanisms of cardiovascular disease.
Research themes focus on nuclear GPCR function in cardiomyocytes, endothelin/β-adrenergic receptor signaling, and p38 MAP kinase regulation during cardiac remodeling. His team employs proteomic approaches to study signaling complexes and develops models for cardiac fibrosis and hypertrophy.
Recent publications examine intracellular angiotensin receptors, MK2/MK3 kinases in myocardial infarction, and transglutaminase implications in heart pathology. Dr. Allen's work bridges molecular pharmacology and cardiac pathophysiology to identify therapeutic targets.
