Brielin Chase Brown

Brielin Chase Brown is an Assistant Professor at the University of Pennsylvania Perelman School of Medicine in the Division of Informatics, Department of Biostatistics, Epidemiology and Informatics, with secondary appointments in the Department of Genetics. Their research focuses on statistical and computational methods in genetics, genomics, and complex traits.

• Education: PhD in Computer Science (UC Berkeley, 2016), BA in Computer Science (University of Virginia, 2011)

Research interests include:

• Causal network inference and Mendelian randomization
• Multi-omic data integration
• Cross-population genetic analysis
• Population structure in genomics

Recent publications highlight advancements in:

• Welch-weighted Egger regression for Mendelian randomization
• Phenome-scale causal network discovery
• Cross-population genetic correlation estimation
• Principal Component Correlation Analysis

Scientific awards include:

• Chancellor’s Fellowship (UC Berkeley)
• NSF GRFP
• Data Science Institute Fellow (Columbia University)

Advising and collaborations:

• Faculty advisor to PhD students Seong Woo Han, Sherry Xie, Nia Abdurezak, Daniel Vo
• Collaborations with Penn Institute for Biomedical Informatics, Penn Center for Causal Inference, and Center for Statistics in Biomedical Big Data

Labs and teams:

• Founder of the Brown Group at UPenn (opened September 2024)
• Postdoctoral researcher at New York Genome Center
• Former computational biologist at Verily Life Sciences