معرفی
Brian Prendergast is a Professor in the Department of Psychology at the University of Chicago's Social Sciences Division. His research focuses on the intersection of biological rhythms, neuroendocrinology, and immune function, particularly through photoperiodic regulation in rodent models.
- NIH R01AI067406 (2005-2017): Biological Rhythms and Immune Function
- NIH F32MH012875 (2002): Neuroendocrine Regulation of Biological Timing
- NIH R56DK102872 (2015-2016): Diet-induced Obesity from Gut Microbial Disruption (Co-PI)
Research themes include:
- Chronobiology: Circadian and ultradian rhythms in mammals
- Seasonal Adaptation: Photoperiodic time measurement and metabolic regulation
- Neuroimmune Interactions: Hypothalamic-pituitary-adrenal axis, seasonal immunological plasticity
- Sex Differences: Pharmacokinetics, behavioral variability, and disease susceptibility
Recent publications (2017-2024) reveal trends in circadian-immune interactions, microbiome effects on host rhythms, and methodological advancements in wavelet analysis. Collaborations span neuroscience, endocrinology, and microbiology disciplines.
Key contributions:
- Established Siberian hamsters as models for seasonal time measurement
- Demonstrated circadian disruption's impact on immune responses
- Challenged assumptions about time-of-day variables in biomedical research
- Elucidated melatonin receptor mechanisms in photoperiod responses
۰مقاله منتشرشده
