Bonnie L Cole

Bonnie L Cole, MD is a Clinical Assistant Professor and Anatomic Pathologist at the University of Washington School of Medicine, affiliated with Seattle Children's Hospital. She has been on staff since August 2011 and is part of the Center for Clinical and Translational Research. Her primary office is located at Seattle Children's Pathology Lab at 4800 Sand Point Way NE, Seattle, WA.

Dr. Cole completed her medical education at the University of Utah School of Medicine in Salt Lake City, UT, and also attended Stanford University. She completed her residency and fellowship in Pathology at the University of Washington in Seattle, WA. She is board certified in Pediatric Pathology and Anatomic/Clinical Pathology.

Dr. Cole's research focuses on pediatric pathology, particularly pediatric brain tumors and CNS embryonal tumors. Her clinical interests include pediatric pathology and laboratory medicine, with significant contributions to neuropathology and molecular characterization of tumors. She has been actively involved in cutting-edge research on CAR T-cell therapy for pediatric CNS tumors and therapeutic approaches for diffuse intrinsic pontine glioma. Her work bridges laboratory medicine with clinical applications to improve diagnostic accuracy and treatment strategies for pediatric cancers.

Analysis of Dr. Cole's publications reveals a strong focus on pediatric neuro-oncology, particularly brain tumors in children. Her research spans from fundamental neuropathology to clinical applications of novel therapies like CAR T-cells. She has contributed significantly to clinical guidelines for pediatric CNS cancers and has published extensively on molecular characterization of tumors. Her work demonstrates a progression from basic pathology to translational research with direct clinical applications, particularly in immunotherapy approaches for difficult-to-treat pediatric brain cancers.

Dr. Cole has been involved in multiple clinical trials and collaborative research projects, including the BrainChild02 phase 1 clinical trial examining CAR T-cell therapy for pediatric CNS tumors. She has contributed to Children's Oncology Group studies and NCCN Clinical Practice Guidelines. Her research has been supported by institutional funding from Seattle Children's and collaborative grants with other pediatric cancer research centers. She actively collaborates with multidisciplinary teams including oncologists, neurosurgeons, and immunotherapy specialists to advance treatments for pediatric brain tumors.

As part of the Center for Clinical and Translational Research at Seattle Children's, Dr. Cole works within a comprehensive research ecosystem focused on translating laboratory discoveries into clinical applications. She collaborates with the Ben Towne Center for Childhood Cancer and Blood Disorders and participates in the neuro-oncology research team. Her work contributes to Seattle Children's position as a leading institution for pediatric cancer research and treatment, particularly in the area of brain tumors and innovative cellular therapies.