Bob Meeusen

Bob Meeusen serves as a Guest Researcher at the Novo Nordisk Foundation Center for Protein Research (CPR), University of Copenhagen, within the Nilsson Group. His work centers on molecular mechanisms of DNA damage tolerance and replication fidelity.

His research interests include:

• Molecular mechanisms of translesion DNA synthesis
• Catalytic and structural roles of DNA polymerases
• Protein-DNA interactions in lesion bypass
• Genomic instability pathways

Recent publications demonstrate a concentrated focus on DNA polymerase κ's dual functionality, merging structural biology with enzymatic analysis to elucidate how cells navigate DNA damage during replication. This work bridges fundamental biochemistry and disease-relevant mutagenesis mechanisms.

Dr. Meeusen collaborates within the Nilsson Group at CPR, which specializes in proteome-wide analyses of DNA repair pathways using advanced mass spectrometry and structural techniques. The group's interdisciplinary approach integrates biophysics, cell biology, and chemical biology to target replication stress in disease contexts.