Beibei Wang

Beibei Wang is a Postdoctoral Fellow affiliated with the Chen Lab at Boston Children's Hospital, focusing on cardiovascular and metabolic disease research. Her work bridges molecular biology, immunology, and translational medicine, with primary interests in atherosclerosis pathogenesis, lipid metabolism regulation, and infectious mechanisms in vascular diseases.

Research Interests: Dr. Wang's studies center on understanding how endocytic adaptors (e.g., Epsins, DAB2) regulate cholesterol metabolism, vascular smooth muscle cell behavior, and endothelial dysfunction in atherosclerosis and diabetes. She investigates disease mechanisms involving Chlamydia pneumoniae infections' role in vascular inflammation and leverages nanotherapy approaches for targeted lipid management.

Key Contributions: Her research highlights Epsin proteins as critical regulators of foam cell formation, atheroma progression, and diabetic wound healing. She has advanced methodologies to target Epsin-mediated pathways using nanotechnology for therapeutic intervention. Recent work explores the crosstalk between Endothelial-to-Mesenchymal Transition (EndoMT) and autophagy in cardiovascular pathologies.

Lab Affiliation: Chen Lab at Boston Children's Hospital, specializing in vascular biology and translational research.