Beatriz Fontoura

Beatriz Fontoura is a Professor in the Department of Cell Biology at the University of Texas Southwestern Medical Center, where she has been faculty since 2005 (progressing from Assistant to full Professor). Her research centers on molecular mechanisms of viral-host interactions, particularly how viruses like influenza and SARS-CoV-2 hijack host mRNA nuclear export machinery.

Education:

• PhD in Pathology, New York University School of Medicine (1991–1996)
• MS in Biochemistry, Paulista School of Medicine, Brazil (1985–1988)
• Postdoctoral training at The Rockefeller University (1996–2001)

Research Focus: Dr. Fontoura investigates nuclear pore dynamics, mRNA export pathways, and viral evasion strategies. Her work integrates structural biology, virology, and drug discovery to identify antiviral targets, including influenza NS1 and SARS-CoV-2 Orf6 proteins. Key themes include TREX-2 complex regulation, interferon signaling disruption, and phase-separated organelles.

Publication Trends: Her 15 most recent articles (2016–2025) reveal a focus on viral interference with nuclear transport, structural studies of host-pathogen interfaces, and chemical inhibitors for antiviral therapy. Recurring topics include SARS-CoV-2 pathogenesis, influenza replication mechanisms, and nuclear speckle function.

Leadership: She directs the Fontoura Laboratory at UT Southwestern, advancing studies in cellular virology and mRNA metabolism.