معرفی
Dr. Ashmeetha Manilall is a Researcher in the Department of Physiology at the University of the Witwatersrand, focusing on molecular mechanisms underlying cardiovascular and reproductive disorders. Her work bridges basic science and clinical implications through innovative animal and cellular models.
Her academic credentials include:
- BSc, University of the Witwatersrand
- BSc Honours, University of the Witwatersrand
- MSc (Med), University of the Witwatersrand
- PhD, University of the Witwatersrand
Research spans cardiovascular physiology (microRNA regulation in hypertension, TNF-α-mediated heart dysfunction, pentraxin-3 in vascular pathology) and reproductive physiology (GNRHR mutations in hypogonadotrophic hypogonadism, comparative studies with PCOS). Recent neurotoxicology work examines nyaope (heroin-based street drug) effects on neuronal cells. Her methodology emphasizes in vivo rat models for hypertension/arthritis and in vitro genetic/epigenetic analyses.
Publication trends (2017-2025) reveal three interconnected trajectories: 1) Inflammatory pathways in early-stage cardiac remodeling (2021-2025), 2) Molecular genetics of reproductive disorders (2017-2019), and 3) Neuropharmacology of South African street drugs (2024). Key journals include American Journal of Physiology-Heart and Circulatory Physiology and Human Reproduction, demonstrating translational impact across cardiology, endocrinology, and neuroscience.
