Aparna Bhaduri

Aparna Bhaduri is a Research Fellow at the University of California, Los Angeles (UCLA), specializing in single-cell genomics and its application to understanding cellular heterogeneity in the nervous system. Her work bridges neuroscience, oncology, and developmental biology, with a focus on glioblastoma, meningioma, and cortical development. Through collaborations with institutions like the David Geffen School of Medicine at UCLA and the Kriegstein Lab at UCSF, Bhaduri has contributed to key insights in neuro-oncology, neurovascular biology, and human-specific brain evolution.

Her research leverages advanced technologies such as brain organoids and single-cell transcriptomics to dissect molecular mechanisms driving tumor resistance, neurodevelopmental disorders like autism, and cellular stress responses. Publications highlight her expertise in NOTCH signaling, LIF signaling, and the role of human-specific genes like NOTCH2NL in cortical neurogenesis. Bhaduri's interdisciplinary approach integrates genomics, bioinformatics, and systems biology to address complex questions in neurodevelopment and disease.

While the scraped data does not explicitly list scientific awards, her leadership in high-impact studies—often as a primary author—underscores her scientific influence. Current projects include modeling 22q11.2 microdeletion syndrome in organoids and investigating radiation-induced cellular plasticity in glioblastoma. Bhaduri's work continues to shape understanding of neural-vascular interactions, tumor stem cell dynamics, and the evolutionary divergence of human brain architecture.