معرفی
Anthony Jaworowski is an Honorary Associate Professor at RMIT University's Department of Health and Biomedical Sciences. His research focuses on immune mechanisms in chronic inflammatory diseases, HIV comorbidities, and innate immunity's role in aging and viral infections. He investigates monocyte and natural killer cell functions, mechanosensitive pathways (e.g., Piezo1), and translational therapies like CAR T-cell engineering. His work spans HIV pathogenesis, cardiovascular inflammation, and malaria immunology. Jaworowski collaborates widely, publishing in top journals like Journal of Immunology and Circulation. He is open to supervising PhD/Masters students in immunology and infectious disease research.
Research Interests:
- Signal transduction in immune cells during chronic inflammation and infections
- Monocyte-mediated atherosclerosis risk in HIV patients
- Adaptive NK cell responses during acute HIV infection
- Mechanosensitive ion channels in vascular inflammation
- Herbal medicine effects on cardiovascular biomarkers
Key Contributions:
- Developed novel HIV latency models using macrophages
- Discovered persistent adaptive NK cell populations despite antiretroviral therapy
- Linked Piezo1 channel activation to monocyte inflammatory responses
- Elucidated HIV envelope epitope expression differences across cell types
His interdisciplinary work integrates clinical immunology with molecular mechanisms, addressing global health challenges in infectious and chronic diseases.
