معرفی
Anthony J. Donato, PhD, MS, serves in the Department of Internal Medicine with a divisional focus in Geriatrics. His academic work centers on translational vascular aging research using human, rodent, and cellular models.
Education:
- Postdoctoral Fellowship, University of Colorado, Department of Integrative Physiology
- Postdoctoral Fellowship, University of California at San Diego, Department of Medicine
- PhD, Texas A&M University
- MS, University of Colorado, Boulder
- BA, University of Colorado, Boulder
Dr. Donato's research investigates vascular aging mechanisms including reduced muscle blood flow during exercise, endothelial dysfunction, and arterial stiffening in older adults. His work identifies cellular pathways activated by lifestyle interventions (exercise, caloric restriction) and explores pharmacological activation of these pathways. Key methodologies include microRNA analysis, ultrasonography, and glycocalyx assessment.
His publication record shows strong focus on endothelial senescence, glycocalyx biology, and metabolic-vascular crosstalk, with recent emphasis on senolytics, Arf6 signaling, and DNA damage in aging vasculature. Trends indicate growing integration of molecular interventions with traditional lifestyle approaches.
No scientific awards were explicitly mentioned in available materials.
Dr. Donato collaborates extensively on translational projects involving vascular function assessment, aging interventions, and metabolic-vascular interactions. His work frequently employs randomized controlled trials and genetic mouse models to dissect mechanisms of age-related vascular decline.
No specific laboratory or team structures were detailed in the source material.
