معرفی
Anna Szekely, MD, is an Assistant Professor in the Department of Neurology at Yale School of Medicine and a key member of the Neurogenetics Program and Program in Neurodevelopment and Regeneration. Her work bridges clinical neurology and genetics with fundamental research in stem cell biology and genomic architecture.
- Semmelweis University Medical Degree (1980)
- Yale Neurology Residency (1997-2000)
- Yale Genetics Research Fellowship (2000)
Dr. Szekely's research explores how genetic programs influence brain health and disease through three major avenues:
- Werner Syndrome Studies: Demonstrated WRN protein's role in oxidative DNA repair, linking aging mechanisms to stem cell genomic stability
- Human Stem Cell Modeling: Developed functional screens for neural differentiation pathways using hESCs/iPSCs, revealing novel transcripts and splicing dynamics
- Hypoxia Effects: Investigates oxygen environment impacts on neural stem cell function for brain repair applications
Her 2023-2025 publications reveal trends in organoid modeling (autism, Tourette's), cell lineage analysis (mutation transmission), and neurogenetic disorders. Scientific awards include NIH-NIA K08 support (2000-2005) and Yale Pepper Center pilot funding. Clinical expertise spans memory disorders, movement disorders, and pediatric neurogenetics.
