Anna Donten

Anna Donten, PhD, is a Researcher at the University of Manchester since 2014, specializing in decision analytic modelling for healthcare economic evaluations. She designs and implements mathematical models to optimize screening programmes and assess cost-effectiveness of health interventions, particularly in breast cancer and stratified medicine. Her work integrates algorithmic approaches with economic frameworks to improve resource allocation in healthcare systems.

Education:

• PhD in Medicine: "The Economic Impact of Precision Medicine in Rheumatology: Targeting the Use of Methotrexate in Early Rheumatoid Arthritis" (University of Manchester, 2022)
• MSc in Computer Sciences and Econometrics (University of Warsaw, 2014)

Research Focus:

• Developing decision-analytic models for risk-stratified screening programmes
• Economic evaluation of Next-Generation Sequencing in congenital cataracts diagnosis
• Algorithmic optimization for cost-effective healthcare interventions
• Validation frameworks for predictive models in breast cancer screening

Key Projects:

• STOpFrac: Discrete Event Simulation for vertebral fracture screening
• ASSURE: Personalised breast cancer screening strategy using risk estimation
• TARDIS Method: Dynamic programming for optimal screening allocation

Collaborations:

• NIHR-funded breast cancer screening cost-effectiveness analysis
• Multi-disciplinary team with Dr. Ewan Gray and Prof. Katherine Payne
• Global health economics initiatives addressing UN SDG 3 (Good Health)

Technical Expertise:

• R programming for model development
• Health economic evaluation methodologies
• Systematic review and meta-analysis techniques
• Discrete event simulation frameworks