Ann S. LaCasce

Ann S. LaCasce, MD, MMSc, is an Associate Professor of Medicine at Harvard Medical School and a leading lymphoma specialist at Dana-Farber Cancer Institute. She directs the Dana-Farber/Mass General Brigham Fellowship in Hematology/Oncology and serves on the Alliance Lymphoma Committee, NCCN Lymphoma Guidelines Panel, and Lymphoma Research Foundation’s Scientific Advisory Committee.

Her educational background includes:

• Medical Degree from Tufts University School of Medicine
• Residency in Internal Medicine at Brigham and Women's Hospital (Chief Medical Resident)
• Fellowship in Hematology & Oncology at Dana-Farber/Partners CancerCare

Dr. LaCasce specializes in lymphoma, chronic lymphocytic leukemia (CLL), and innovative treatments including CAR T-cell therapy and stem cell transplantation. Her clinical focus extends to rare presentations like CNS lymphoma and MALT lymphoma in the brain, where she integrates cutting-edge therapies with compassionate patient care. She actively shapes national treatment guidelines through her committee leadership.

As Fellowship Director, she mentors future oncologists while maintaining active clinical practice. Patient testimonials consistently highlight her expertise, empathetic communication, and ability to navigate complex cases. Her 564 five-star ratings reflect exceptional patient satisfaction.

Dr. LaCasce operates within Dana-Farber's integrated oncology ecosystem, collaborating across the Lymphoma Program, CNS Lymphoma Center, Center for CLL, and Stem Cell Transplantation program to deliver multidisciplinary care for hematologic malignancies.